Comparative evaluation of the biological effect of native and synthesized peptides
Biologically active peptides are considered as preventive and therapeutic agents for various diseases. Due to the high cost and complexity of isolating native peptides for use in pharmaceuticals, synthetically produced peptides are increasingly being used in dietary supplements. The aim of the research is to confirm the similarity and biological activity of synthesized peptides compared to native peptides. Synthesized and native peptides from bovine colostrum with the code names T1.1 and mpT2...
Kant über inneren Sinn, Zeitanschauung und Selbstaffektion
... inner sense and point out that inner sense as a receptive faculty depends on self-affection. In so doing, I emphasise that self-affection includes both a pure and an empirical aspect which corresponds to Kant’s distinction between the transcendental synthesis of imagination and the empirical synthesis of apprehension. Then, I focus on the pure aspect and argue that the conceptualising function involved in the pure self-affection is decisive for the generation of formal intuition. In particular, I ...
Characterization and use of synthesized antimicrobial peptide in the composition of biodegradable food film
One direction in the development of food packaging involves the use of biodegradable safe materials along with antimicrobial agents. Among the promising prescribed ingredients for biodegradable films are biopeptides with antimicrobial properties. The research goal was to develop a biodegradable food film using a synthesized antimicrobial peptide. The objects of the study were the peptide, test strains of C. albicans, Escherichia coli, and Bacillus subtilis. The confirmation of the purity and primary...
Reactions of dibenzothiazine amination of quinone derivatives on a «copper film»
... Фармацевтическая химия : учеб. пособие : в 2 ч. 4-е изд., перераб. и доп. М., 2007.
4. Ojha N. K., Zyryanov G. V., Majee A. et al. Copper nanoparticles as inexpensive and efficient catalyst: A valuable contribution in organic synthesis // Coordination Chemistry Reviews. 2017. Vol. 353. P. 1—57.
5. Salavati-Niasari M., Davar F., Mir N. Synthesis and characterization of metallic copper nanoparticles via thermal decomposition // Polyhedron. 2008. Vol. 27, iss. 17. P. 3514—3518....
The mythical-historical images of Bruno Schulz’s ‘Spring’ in the context of Kafka’s mythologism
Myths and history are different but related forms of consciousness. They date back to the archaic and new periods of world history. New forms of synthesis between history and myths translated in the ‘mythical-historical imagery’ of the 20th-century art. For the first time in the history of world culture, modernism has created a synthesis between the seemingly divergent elements — history ...
Physical and chemical characteristics, antioxidant properties and the effect of the newly synthesized peptide on lipid deposition in cells
A novel peptide, CG-16, with the sequence CHAECGAACKEFCLEG, was designed and synthesized. Studies were conducted to assess its physicochemical properties, antioxidant activity, and effects on lipid deposition in cells in an in vitro experiment. It was established that the CG-16 peptide does not contain antigenic determinants. A search across the PeptideAtlas, UniProt, and the National Center for Biotechnology Information (NCBI) databases confirmed the uniqueness of the synthesized peptide. The prediction...
Synthesis of some nitrogen-containing heterocycles based on benzotriazole and bromo-substituted and condensed quinones
In this article, we describe the process of obtaining nitrogen-containing heterocycles based on benzotriazole and bromo-substituted and condensed quinones. As known, nitrogen-containing heterocyclic compounds containing amide function are used in the synthesis of biologically active substances. One can expect products synthesized with quinones and heterocyclic amines of the benzotriazole series to have a wide spectrum of biological activity and other useful properties.
1. Monbaliu J.-C. M. The Chemistry ...
The phenomenon of heterogeneity of the speech subject in German retrospective discourse
....31912/pvrli-2023.2.2 (in Russ.).
Zubkova, L., 2016 Teoriya yazyka v ee razvitii: ot naturotsentrizma k logotsentrizmu cherez sintez k lingvotsentrizmu i k novomu sintezu [Theory of language in its develop- ment: from naturcentrism to logocentrism through synthesis to linguacentrism and to a new synthesis]. Moscow (in Russ.).
A synthesis of genres in Andrey Bolotov’s memoirs
... shows that all those elements were not combined mechanically. A well-read and stylistically sensitive author, he was guided by an intuitive sense of appropriateness of each technique depending on the object of description and thus achieved a genuine synthesis of genres. Finally, it is concluded that this intuition and a clear understanding that his task was a thorough description of his life as a record for posterity translated in the literary finesse of Bolotov’s texts and their appeal to the ...
Studies into the history of Russian Neo-Kantianism in Poland
... Szczepanczyk]. Kielce, p. 7—33.
24. Bohun M. 2012, Nowa ontologia czy «prywatna metafizyka»? Kilka uwag na marginesie «syntezy krytycznej» Fiodora Stiepuna [The new ontology or „the private metaphysics”? Some remarks on Fyodor Stepun’s „critical synthesis”] // Postneokantyzm — ontologizm / pod red. B. Czardybon, L. Augustyna, M. Bohuna. Estetyka i Krytyka [Post-neo-Kantianism — ontologism / eds. B. Czardybon, L. Augustyn, M. Bohun. Aesthetics and Criticism]. № 26, p. 295—307.
25. Bohun ...
Subjective modality of the literary text: ontological status in author’s conception of the world
... ontological status of the subjective modality of a literary text as a component of the author’s concept of the world. The material for the study is the literary text of the essay “Caucasian” by M.Yu. Lermontov as a genre that demonstrates a complex synthesis of various zones of implementation of subjective modality. The author’s concept, embodied with the help of various means of subjective modality, is determined by the writer’s system of values, his spiritual experience, and his aesthetic ...
Transdisciplinarity as a mechanism of educational innovations: synthesizing pedagogical experience
Due to the relatively recent emergence of transdisciplinarity in the educational sphere, the mechanisms of innovations, whose philosophical basis it constitutes, remain insufficiently studied. The aim of this article is to present a systematic experience in which transdisciplinarity serves as a mechanism for educational innovations and contributes to achieving new quality educational outcomes or obtaining more reliable, convenient, and functional pedagogical developments. The results include the...
Teacher training for the formation of functional literacy in primary school: the problem of individualisation
... of a teacher’s professional role, the evolving nature of a future teacher’s individuality and the importance of cultivating the capacity for making meaningful professional choices. Theoretical sources were explored using methods of analysis and synthesis, while empirical research involved the group discussion method. The study emphasised the importance of focused efforts to cultivate among students of pedagogical universities the professional competencies needed for an individualised educational ...
Universal digital competences: higher education personalisation for digital economy
... Russian standards behind the current demands of the labor market and international trends: the absence of requirements for working with artificial intelligence, machine learning, ethical aspects of data, and adaptability to technologies. Based on a synthesis of international practices, a model of digital competency personalization for distance learning conditions is proposed, which includes data literacy, digital ecosystem management, and legal awareness. The necessity of personalizing educational ...
An investigative action as a set of procedural measures and an element of the system in the structure of the institution of evidence
... for new perspectives that allow a somewhat different consideration of investigative actions as a legal phenomenon, which determined the aim of this article. To achieve this aim, along with general scientific methods (logical, comparative analysis, synthesis), specific legal methods (interpretation of legal norms and formal-legal analysis) were also applied. The empirical method formed the basis for addressing law enforcement practice. This made it possible to determine the place of the system ...
Performing verification actions before initiating a criminal case: theory and practice
... operational-search measure, and search and seizure as investigative actions. The philosophical foundation is dialectical materialism, which presupposes the study of all phenomena in their totality and systemic interconnection. The study employs methods of synthesis and analysis, induction and deduction, as well as special methods of research in the field of legal science. The main problems concerning verification actions are examined, including the determination of their legal nature, the clarification ...
FROM THE EDITOR
Due to technical reasons, several articles originally intended for the thematic issue “Pragmalinguistics: In Search of Synthesis” (Slovo.ru: Baltic Accent, 2025, No. 2), prepared by the editorial team in collaboration with guest co-editors V. V. Feshchenko, I. V. Zykova, and O. V. Sokolova, have been carried over into the present issue. With this release, we conclude ...
The State Academy of Artistic Sciences versus Petrograd formalism: Verse theory. II. On Zhirmunsky’s “Rhyme, its history and theory”
... Aesthetic Theory of the 1920s]. Vol. I. Moscow, pp. 29—43 (in Russ.).
Plotnikov, N. S., 2021. Beyond encyclopedia: A short story of concept of “form”. In: N. Sazonov and A. Hennig, eds.
Sintez sovremennosti. Ruiny GAKhN i postdistsiplinarnost'
[Synthesis of modernity. The ruins of GAKhN and postdisciplinarity]. Moscow, pp. 239—250 (in Russ.).
Polilova, V., 2011. Debates around “Khudozhestvennaya forma” and “Ars Poetica” volumes: Boris Yarkho and OPOYaZ.
Studia Slavica: sbornik rabot ...
Who and how produces the future (Alexander Fedorov’s new philosophy of common cause)
...
Tulchinskii, G. L., 2020.
Filosofiya postupka: samoopredelenie lichnosti v sovremennom obshchestve
[Philosophy of action: self-determination of personality in modern society]. St. Petersburg, 826 p. (in Russ.).
Tulchinskii, G. L., 2021. Value-normative synthesis of knowledge. In:
Mir cheloveka: normativnoe izmerenie — 7.0
[The human world: normative dimension — 7.0].
Saratov, pp. 226—243 (in Russ.).
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Chelovecheskoe ponimanie
[Human understanding]. Moscow, 328 p. (in ...
On multiple semiotics integrally, aspectively and concretely
..., Tartu, pp. 11—24.
Kull, K., 2021. Natural selection and self-organization do not make meaning, while the agent’s choice does.
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Kull, K., 2022. The aim of extended synthesis is to include semiosis.
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Lacková, L. and Faltýnek, D., 2021. The lower threshold as a unifying principle between Code Biology and Biosemiotics....
Unveiling the unseen: the challenge of phenomenological conceptual untranslatables
... Nefedova, L. and Gillespie, G., 2016. From Function to System: Advances in Choosing a Matrix Structure of the Translation Process. Russian Journal of Linguistics, 20 (3), pp. 230—242.
Remkhe, I. N. and Nefedova, L. A., 2022. The dialectics of the synthesis of cognition and the translation industry. Bulletin of Chelyabinsk State University, 3 (461), pp. 105—114,
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Schwieter, J. W. and Ferreira, A., eds., 2017. Psycholinguistic and Cognitive ...
‘Hallberd of Balderdash’ or an attempt at decoding Alexei Chicherin’s construemes (dedicated to the 100th anniversary of their publication)
This paper is the first attempt to interpret the visual 'construemes' by the constructivist poet Alexei N. Chicherin, published in the anthology Mena vsekh (Moscow, 1924). 'Construemes' can be considered the most enigmatic artefacts of the Russian avant-garde. Although 'construemes' can be easily confused with meaningless visual zaum ('the transrational'), Chicherin's actions and the very nature of his personality prevent one from interpreting 'construemes' as actionist endeavours to scandalise...
Language of digital poetry description: the semiotic and literary aspects
....net/publication/296943882_Digital_poetry_beyond_the_metaphy
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Zapadnoevropeiskii simvolizm i problema sinteza iskusstv: opyt intermedial'nogo analiza
[Western European symbolism and the problem of synthesis of arts: experience of intermedial analysis]. St. Petersburg (in Russ.).
Tishunina, N. V., 2003. Interaction of arts in a literary work as a problem of comparative literature.
Filologicheskie nauki
[Philological sciences], 1, pp. 19—26 (in ...
Semio-poiesis: on the birth of the semiosphere from the biosphere
... Biological and Epistemological Perspectives on Selection and Self-Organization
. Dordrecht: Kluwer, pp. 281—293.
Hoffmeyer, J., 2007. Semiotic scaffolding of living systems. In: M. Barbieri, ed.
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duction to Biosemiotics: The New Biological Synthesis
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A. Uspenskii. Perepiska 1964—1993
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Meaning of proper names in contexts of attitudes: de re naming and fictions
... Philosophical Quarterly
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Maier, E., 2017. Fictional names in psychologistic semantics.
Theoretical Linguistics
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B., 2018. Semiotic facts.
Logiko-filosofskie shtudii
[Logical and philosophical studies], 16 (4), pp. 311—334
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Mikirtumov, I.
B., 2020.
The logic of the naming relation ...
Sootechestvenniki (compatriots) in the 19th century: semantic profile based on the data of the National Corpus of the Russian language
... other gravitates to ethnicity since it is used to refer to Russians. With the strengthening of state institutions in Russia, the first meaning was bound to dominate and it did at the beginning of the 19th century. However, one should speak not about the synthesis, but rather about the discordance of the two meanings. In the 19th century, another meaning developed in the semantic structure of the word: ethnic Russians living abroad. Gradually, the word acquired new evaluative meanings, while negative ...
The concepts of citizenship and estate in Russian history — continuity and / or intermittence
... Paradoxically, in Soviet Russia citizenship was defined through its absence, through what it was not. The concepts of citizenship and classhood during the Imperial and Soviet periods often coexisted, complementing each other and forming a bizarre synthesis of traditional and modern approaches to the interpretation of the concept of citizenship.
Pevzner, M. B., 2003. Abbat Siies: ot Burbonov k Bonapartu [Abbot Sieyès: from the Bourbons to Bonaparte]. St. Petersburg (in Russ.).
Babel, I. Rech ...
‘Reaching out’ beyond the text: philosophical notes
In this article, I define the concept of text and briefly discuss the related concepts of speech and discourse. I demonstrate how the humanities treat texts and examine the structural-semiotic and the hermeneutic approach. Further, I identify both the differences between these approaches and the similarities in the ways they interpret texts. I argue that the philosophical approach seeks to go beyond the text as far as possible without leaving it altogether and stress that the divide between the...
Textonics: an introduction to electronic philology
Digital philology studies texts and textuality in electronic networks and the ways of their reading, writing and transformation. Electronic texts are much more fluid and transformable than paper texts and oral utterances. Textonics is a combination of theoretical and practical work with digital texts, the use of the Internet and all the capabilities of computer technology to create new sign ensembles, to develop new genres of intellectual creativity, and to rethink and reorganize existing textual...
The problem of meaning in Social Semiotics: Max Weber today
... not only in linguistics amd semiotics, but also in M. Weber's theory: thesubject of sociology is the understanding of “the meaning of behavior”. Based on the Weber’s definitions and their possible modification, we suggest the transdisciplinary synthesis around the study of the problem of meanings and their manifestation. Meaning production is understood as a result of the conjunction of linguistic and extralinguistic systems in the process of social interaction and communication. This allows ...
Cultural Transfer and Etymology
This article considers the synthesis of information transference in space and time and examines the etymology of Indo-European lexis. The author pays attention to the origin of the lexis connected with the ‘bear’ semantics. The bear taboo was developing against the background ...
The ‘secret portrait’ in Eastern Slavic religious paintings on the threshold of modernity: The southwestern accent
This article examines the first attempts at introducing realistic portraits into Eastern European religious paintings. The author identifies stages in the development of this trend and describes aspects of cultural synthesis embodied in a portrait as the first secular genre of painting. A distinctive feature of this process is depicting an actual person in a religious context.
1. Александрович В. С. Портретная живопись во Львове ...
Tool-Kit for Ethical Analysis of Video Games: Answer to the Challenges of the New Enlightenment
... of Gaming & Virtual Worlds, 4(3), pp. 215-37.
https://doi.org/10.1386/jgvw.4.3.215_1
.
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Bryushinkin, V. N., 2013. The Transcendental Synthesis of World Models in Intellectual Systems. In: S. Bacin, A. Ferrarin, Cl. La Rocca and M. Ruffing, eds. 2013. Kant und die Philosophie in weltbürgerlicher Absicht: Akten des XI. Kant-Kongresses 2010. Berlin & Boston: De Gruyter, pp. 691-702. ...
Nikolay Fyodorov’s Attempt to Link Aristotelian and Kantian Natural Teleology to the Project of Nature Regulation
... Scientists, Spiritual and Secular, to Believers and Non-Believers). In: N.F. Fyodorov, 1995. Sobranie sochineniy v 4 tomakh [Collected Works in 4 Volumes]. Volume 1. Moscow: Progress, pp. 35-308. (In Rus.)
Fyodorov, N. F., 1995b. Supramoralism, or Universal Synthesis (i.e., Universal Unity). In: N. F. Fyodorov, 1995. Sobranie sochineniy v 4 tomakh [Collected Works in 4 Volumes]. Volume 1. Moscow: Progress, pp. 388-441. (In Rus.)
Fyodorov, N. F., 1995c. Three Reasons and the One Reason. In: N. F. Fyodorov,...
Apology of Human Existence vs “Ideal Homicide”: S.L. Frank’s Anthropological Project.
... warning against turning Kant’s philosophy into a dogma and allowing for diverse interpretations of Kant (P. Natorp), Frank saw Kant not as a critic and “destroyer” of metaphysics, but as a thinker who laid the foundations of a new metaphysical synthesis. He set himself the task of “transforming” the Kantian philosophy into a new metaphysical system proceeding from the foundational principles of critical thinking. As a result, he managed to overcome the abstract concept of the human being ...
Types of Representational Content in Kant
...
Griffith, A. M., 2012. Perception and the Categories: A Conceptualist Reading of Kant’s Critique of Pure Reason. European Journal of Philosophy, 20(2), pp. 193-222.
Grüne, S., 2009. Blinde Anschauung. Die Rolle von Begriffen in Kants Theorie Sinnlicher Synthesis. Frankfurt am Mein: Klostermann.
Gunther, Y. H., 2003. General Introduction. In: Y. H. Gunther, ed. 2003. Essays on Nonconceptual Content. Cambridge: Cambridge University Press, pp. 1-19.
Hanna, R., 2001. Kant and the Foundations of Analytic ...
Kant’s Dissertation for the Master’s Degree On Fire and the Transformations of his Ideas of Ethereal Matter
... System? Journal for the History of Philosophy, 25, pp. 533-555.
Förster, E., 1989. Kants Selbstsetzungslehre. In: E. Förster, 1989. Kant’s Transcendental Deductions. Stanford: Stanford University Press, pp. 217-238.
Förster, E., 2000. Kant’s Final Synthesis. An Essay on the Opus Postumum. Cambridge, Mass.: Harvard University Press.
Friedman, M., 1992. Kant and the Exact Sciences. Cambridge, Mass.; London: Harvard University Press.
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...
Darwinism as the Missing Link in Kant’s Critical Philosophy
... which would offer a more solid scientific grounding for his entire system. I believe that Darwinism is such a link which bolsters the central but ungrounded thesis of the Critique of Pure Reason on the existence of a priori synthetic judgments. The synthesis of Darwinism and critical philosophy dictates, however, a substantial restructuring of the latter since some of its key elements prove to be weak in the light of modern studies and need to be revised or even reversed. The first reversal explored ...
Kant’s appearance as an objective-objectual [gegenständlich] representation
... hand, Kant’s transcendentalism rests on the distinction between things-in-themselves and appearances. On the other hand, our method of cognition is representative in that is based on representations — subjective and objective (objectual) ones. A synthesis of the above considerations suggests that Kant’s transcendentalism rests on the [conceptual] triad — ‘[objective] object (thing-in-itself; Ding an sich) —appearance (Erscheinung) — and [mental] representation (Vorstellung)’. Kant’s ...
Transcendental logic and analytic of concepts
... и учение Канта. СПб., 1997.
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10. Gerhardt V., Kaulbach F. Kant. Darmstadt: Wissenschaftliche Buchgesellschaft, 1979.
11. Hoppe H. Synthesis bei Kant: Das Probleme der Verbindung von Vorstellungen und ihrer Gegenstandsbeziehung in der “Kritik der reinen Vernunft”. B.; N. Y., 1983.
12. Howell R. Kant’s Transcendental Deduction: An Analysis of Main Themes in His Critical Philosophy....
Bogdan Kistiakovy’s Project of “State of the Future” as Synthesis of the Ideas of Liberalism and Socialism
This article is devoted to the correlation between liberal and socialist ideas in the social and philosophical conception of the prominent methodologist of social sciences and a Neo-Kantian legal theorist Bogdan Kistyakovsky. The author stresses the uncertainty of both the definition of liberalism and the principles behind attributing concrete thinkers to this movement. The article emphasises the inconsistency of classifying Kistyakovsky’s socio-philosophical concept as liberal. The analysis performed...