2024 Issue №3

The development of an antiplatelet peptide was conducted using proteomic databases and the Cybase cyclic peptide database. Toxicity prediction was carried out on the ADMETlab 3.0 platform. The framework used was the cyclic peptide PLP-5, listed under number 1375 in the Cybase database. A new peptide with the amino acid sequence QLSNGLFVDYLWW was obtained. According to the peptide bioactivity predictor, it has a bioactivity level of 0.81968 units, with a maximum of 1. The peptide does not cause acute toxicity when administered orally, is non-toxic to the heart, liver, eye mucosa, and respiratory tract, is non-mutagenic, and non-cytotoxic. This allows it to be recommended as a functional ingredient for specialized food products, provided its effectiveness is confirmed in in vitro experiments.

More than half of Russia’s coal is extracted in the Kemerovo region. Unfortunately, coal mining causes significant environmental damage and is one of the most hazardous human activities. Coal dumps contribute to the degradation of vegetation, fauna, agricultural, and forest lands. Traditional reclamation methods have shown limited effectiveness and require improvement. Therefore, the aim of this article is to develop preliminary technological solutions for the biological reclamation of a coal mine dump in the Kemerovo region, located in the Prokopyevsky district, based on the area’s ecological and geographical parameters. For this purpose, aerial photography using a DJI Matrice 30 and laser scanning with a Slam scanner (robotslam lite) were conducted, and the climatic and botanical-geographical characteristics of the area were studied. As a result of the data analysis, it was determined that, overall, the natural and climatic conditions of the area are favorable and allow for reclamation work aimed at creating forest and grassy plantings for sanitary-protective, forestry, and agricultural purposes. In the first stage, it is necessary to create a favorable root zone using potentially fertile rocks and humus-rich materials from fertile soil layers. In the biological stage of reclamation, local tree and shrub species, as well as fruit and berry crops, are planned to be used to form the soil-plant layer.

Currently, callus cultures of medicinal plants are actively used for the production of important biologically active compounds. Investigating conditions that enhance the biosynthesis of these compounds in callus cultures is highly relevant. This article examines the influence of various concentrations of phenylalanine and tyrosine (1—500 µM) on the content of phenolic compounds and the antioxidant activity of three callus cultures of Hyssopus officinalis L. It was found that the addition of phenylalanine at a concentration of 10 µM and tyrosine at a concentration of 100 µM to the nutrient media leads to an increase in the content of phenolic compounds and hydroxycinnamic acids in the callus cultures. An increase in the antioxidant activity of the extracts from the studied callus cultures was recorded at phenylalanine concentrations of 10 and 100 µM, as well as tyrosine concentrations of 1, 10, and 100 µM in the nutrient media.

The article is dedicated to summarizing the results of the inventory of the plant collection at the Botanical Garden of the Immanuel Kant Baltic Federal University (IKBFU). Over the past 20 years, the taxonomic composition has nearly doubled. New collection sections have been created (for fruit plants, magnolias, lilacs, rhododendrons, medicinal plants, and others), and the reconstruction of the greenhouse collection has significantly enriched the assortment of tropical, subtropical, and arid plants. The inventory was conducted using standard methodologies applied for plant accounting in botanical gardens. The plant names comply with the requirements of the International Code of Botanical Nomenclature (2017), taking into account the modern International Taxonomic System of Classification (APG IV) and the database of the International Plant Taxonomy Encyclopedic Internet Project (The Plant List). As a result of the inventory of the taxonomic composition of the collections, a new “Catalogue of Plants of the Botanical Garden of IKBFU for the 120th Anniversary of its Founding” has been prepared for publication. The catalogue provides an informational resource on the biodiversity of the garden’s collection, a systematic characterization of taxa, and the scientific organization of the objects.