Perspectives of using of composite nano- and micromaterials as agents for biomedical applications
... advanced techniques in biomedicine, bionanotechnology, and nanomedicine. In this context, there is a need to assess the toxicological characteristics of materials as well as develop methods for their therapeutic use. A study was conducted to evaluate the cytotoxicity of composite nanoparticles (nanostars) and micromaterials (microdisks) against Jurkat, Huh7 cell cultures, and human mononuclear cells in in vitro conditions. A concentration-dependent cytotoxic effect of nanoparticles was observed. At the ...
Development and prediction of toxicity of a new antiplatelet food peptide
... recommended as a functional ingredient for specialized food products, provided its effectiveness is confirmed in in vitro experiments.
Tikhonov S.L., Tikhonovа N.V.
cyclic peptides, antithrombotic properties, biological activity, toxicity, cytotoxicity
81-88
10.5922/vestniknat-2024-3-6
Comparative evaluation of the biological effect of native and synthesized peptides
... induced type 2 diabetes and the antioxidant activity of synthesized and natural peptide T1.1 have been demonstrated.
Tikhonov S.L., Tikhonova N.V., Ulitina E.A.
cow colostrum peptides, synthesized peptides, molecular weight, amino acid sequence, cytotoxicity, antihyperglycemic effect, antioxidant activity
106-117
10.5922/gikbfu-2023-3-8