2023 Issue №3

The Kemerovo Region is situated in the Central deciduous-forest, forest-steppe, and steppe soil-bioclimate regions of the Subboreal temperate soil-bioclimate zone. The researched territory of the Kazachensky motor dumping site, which is within the Taldinsky coal mine, according to the soil-geographic zoning data, is located at the intersection of two soil-geographic districts — Kemerovo-Prokopyevsky and Kuznetsko-Alatausky. On the studied technogenic landscape, identified areas are characterized by the presence of technogenic com­plexes with young soil formations. On the surface of the dumping site, signs of initial soil formation are observed. The restoration of the soil cover is at an initial stage, where only young soil-like bodies, embryosols, are found. The soils of the Kemerovo Region, Kuzbass, are identified on the following morphological features: the thickness of the humus horizon is up to 30 cm, a clearly expressed crumbly-granular structure, heavy loamy; the transitional horizon is unevenly colored, with signs of gleying, heavy loamy; the presence of a small amount of sandy fractions throughout the profile; soil-forming rock; stratified sandy loam or loam.

Biologically active peptides are considered as preventive and therapeutic agents for vari­ous diseases. Due to the high cost and complexity of isolating native peptides for use in phar­maceuticals, synthetically produced peptides are increasingly being used in dietary supple­ments. The aim of the research is to confirm the similarity and biological activity of synthe­sized peptides compared to native peptides. Synthesized and native peptides from bovine co­lostrum with the code names T1.1 and mpT2 were used as the objects of the study. The pep­tides were synthesized using the solid-phase method. Peptide T1.1 is similar to the peptide «POSSUM_01-POSSUM-C-EMBRYO-2KB», the biological activity of which has not been studied. Peptide mpT2 is similar to the anti-diabetic peptide «LL-16 Alytes obstetricans». It has been proven that the synthesized peptides do not differ from natural ones in terms of physical and chemical characteristics. Both synthesized and natural peptides are non-toxic. The anti-diabetic effect of natural and synthesized peptide mpT2 on animals with induced type 2 diabetes and the antioxidant activity of synthesized and natural peptide T1.1 have been demonstrated.