The ulrasonographic semiotics of diffuse liver disease: Verification using the point shear-wave elastography
AbstractThis article estimates the severity of ultrasonographic changes in the liver at different stages of fibrosis. Sixty-three patients underwent B-mode ultrasound scanning of the spleen and the liver and ARFI-elastography of the liver. Elastography measured the shear wave speed from the 9th, 8th, and 7th intercostal spaces in the anterior axillary line at a depth of 6.0 cm from the skin surface. It was established that patients with fibrosis stages F1 and F2 exhibited from one to four and those with fibrosis F3 and F4 from three to eleven ultrasonographic symptoms. In most cases, as fibrosis progressed, the number of ultrasonographic symptoms increased. Twelve patients with elastographyconfirmed fibrosis stage F2-F4 did not exhibit any apparent ultrasonographic symptoms. Within this group, 42 % of the patients with fibrosis stage F3 and F4 – or 8 % of all the patients – did not exhibit any ultrasonographic symptoms. One or two ultrasonographic symptoms appeared in 12 % of the patients with fibrosis stage F3-F4. It is concluded that even a single ultrasonographic symptom should be interpreted by the ultrasound specialist as a possible sign of fibrosis or cirrhosis.