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... obtained. We performed a whole body PET/CT scan and a myelogram to con­firm the diagnosis. Since therapy was ineffective, we conducted two courses of second-line therapy (R-ICE) and received a partial response. Further, alloge­neic hematopoietic stem cell transplantation was recommended. After two R-ICE courses, the patient received supportive polychemotherapy (Rituximab + + Gem­zar), without progression. Six months later, the patient's condition wors­ened. We performed spinal puncture and diagnosed ...

... медико-биологический вестник имени академика И. П. Павлова. 2014. № 3. С. 56—60. 5. Ярилин А. А. Иммунология : уУчебник. М., 2010. 6. Larbi A., Fulop T. From «Truly Naïve» to «Exhausted Senescent» T Cells: When Markers Predict Functionality // Cytometry Part A. 2014. Vol. 85A. P. 25—35. 7. Briend E., Colle J. H., Fontan E. et al. Human glycoprotein HGP92 induces cytokine synthesis in mouse mononuclear phagocytes // Int Immunol. 1995. Vol. 7. P....

This article focuses on the endocrine function in flatworms. It is implemented with the help of two groups of hormones. Several centres of neurosecretory cell localisation were discovered in the nervous system of flatworms. The hormonal signal is transmitted with the help of adenylate cyclase system, which is peculiar to vertebrates. Endogenous steroids – sex steroids and glycocorticoids — were detected ...

... and hierarchy of genetic mechanisms for the implementation of genetic information in embryogenesis, as it is seen in systems biology. Antebi, Y. E., Linton, J. M., Klumpe, H. et al., 2017. Combinatorial Signal Per­cep­tion in the BMP Pathway. Cell , 170 (6), pp. 1184—1196, https://doi.org/10.1016/j . cell.2017.08.015. Armingol, E., Officer, A., Harismendy, O. et al., 2021. Deciphering cell—cell interactions and communication from gene expression. Nature Reviews Genetics , 22, pp. 71—88,...

The article gives morphometric characteristics of thymic mast cells of rats supplied with drinking water for 10 months in a concentration of 10 mg/l in correlation to silicon. It has been shown that the amount of mast cells does not change in interlobular cortical thymus septa with this type of exposure, however,...

Bacterial cellulose (BC) is a biomaterial produced by certain bacteria that possesses unique properties, distinguishing it from plant-derived cellulose by its purity, high crystallinity, excellent biocompatibility, and superior water-holding capacity. Due to these advantages, BC is increasingly used in various industrial applications. However, large-scale production of BC is limited, particularly by the high cost of the culture medium. This review presents an analysis of scientific data and official...

... productivity of the fermentation process. The advantages of such compounds include minimal consumption, stability during storage, and lower cost compared to natural growth stimulants. The aim of this study was to investigate the effects of protatrans on cell development and intracellular protein biosynthesis in the yeast Candida ethanolica. It was established that the effects of protatrans depend on the concentrations of these compounds as well as the method of their application (separate or combined)....

This article considers a number of cell indicators of the organism that can be potentially used for the individual monitoring of selecting graduated exercises, which contributes to an increase in the efficiency of athlete’s training. A number of the most reactive indicators (hematologic ...

A novel peptide, CG-16, with the sequence CHAECGAACKEFCLEG, was designed and synthesized. Studies were conducted to assess its physicochemical properties, antioxidant activity, and effects on lipid deposition in cells in an in vitro experiment. It was established that the CG-16 peptide does not contain antigenic determinants. A search across the PeptideAtlas, UniProt, and the National Center for Biotechnology Information (NCBI) databases confirmed the uniqueness ...

... Gync. 2012. Vol. 120, № 5. P. 1160—1175. 25. Van Roy F. Beyond E-cadherin: roles of other cadherin superfamily members in cancer // Nat. Rev. Can. 2014. Vol. 14. P. 121—134. 26. Van Roy F., Berx G. The cell-cell adhesion molecule E-cadherin // Cell. Mol. Life Sci. 2008. Vol. 65, № 23. P. 3756—3788. 27. Varma R. The effectiveness of a levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of endometrial hyperplasia — a long-term follow-up study // Eur. J. Obstet. Gynecol....

... Nagabhushanam R., Sarojini К. Vertebrat-type hormones in crustaceans: localization, identification and functional signification // Zool. Sci. 1993. Vol. 10, № 1. P. 13—29. 3. Boer H. H., Montagne-Wajer C., Smith F. G. Funcional morhyology light yellow cell and yellow cell (sodium in flax-stimulating peptide) neuroendocrine systems of the pond snail Lymnea stagnalis //Cell and Tissue Res. 1994. Vol. 275, № 2. P. 361—368. 4. Кудикина Н. П. Экологические аспекты динамики ...

... the innovative development of the region. The author examines the near-term trends in the telecommunications market of the Kaliningrad region. The article offers an analysis of principal investment areas, namely: the expansion of the 3rd generation cell network, expansion of broadband network using FTTB (Fiber To The Building), Wi-Fi and Wi-MAX and LTE (4rd generation cell network) technologies. The author emphasizes the importance of M&A (Mergers and Acquisitions) for the sector as an investment ...

To maintain the normal state of the immune system, the processes of cell proliferation must be strictly regulated and balanced by the processes of apoptotic death to prevent the development of autoimmune and neoplastic reactions. T-lymphocytes of immune memory are under strict control from the immune system. The role ...

Women are the core population group responsible for new HIV infections and the persistence of the HIV pandemic. A key determinant of susceptibility to HIV infection is the composition of the vaginal microbiome, which can influence the local immune cell population and inflammation status. While a low diversity microbial composition dominated by Lactobacillus crispatus is associated with a reduced risk of HIV infection, a high microbial diversity environment associated with bacterial vaginosis increases ...

... active acidity of the suspension of all the studied samples of microalgae have different values, but all the studied microalgae is found to grow and actively develop in an alkaline environment. It has been shown that during the cultivation of microalgae cell culture, the largest amount of protein accumulates in Arthrospira platensis. The amount of protein in the cultivation of Dunaliella salina and Chlorella vulgaris cell cultures was approximately the same. It is planned to create dietary supplements ...

The production of bioethanol from non-food feedstock is considered to be a promising alternative to conventional ethanol production from food crops. However, a number of significant technological drawbacks does not allow the industrial production of bioethanol. There is the problem of screening the most effective microorganisms-producers in particular. Due to multicomponent composition of substrate, the use of several strains of microorganisms is considered to be more effective than that of one strain...

... бронхиальная астма, диагностика, лечение и профилактика. М., 2011. 6. Voelkel N., Spiegel S. Why is effective treatment of asthma so difficult? An integrated systems biology hypothesis of asthma // Immunol Cell Biol. 2009. № 87 (8).P. 601—605. 7. Глобальная стратегия лечения и профилактики бронхиальной астмы /под ред. А. C. Белевского. М., 2012. 8. Proceedings of the ATS workshop ...

... the formation of immunological memory are numerous and varied. The steroid hormones are considered the most abundant group of biologically active agents. The influence of these agents on proliferation, differentiation and apoptosis of immune system cells is being intensively studied. This review analyses the data on the role of steroid hormones in the immune memory regulation obtained in the recent researches. Litvionova L. S.,Seledtsov V. I., Schupletsova V. V., Gutsol A. A., Anischenk Ye. ...

... examination of its metalanguage essence. Crossword descriptions reflect the outcomes of metalanguage consciousness operations, which aim to depict the elements of the semantics of encrypted nominations. The unit of research is the crossword puzzle cell — the basic structural unit, which is formed by the unity of the description and the encrypted nomination. A description containing information about the encoded word forms a verbalized part of the crossword puzzle cell, and the encoded nomination ...

This article focuses on Rosenzweig’s major work The Star of Redemption. The author attempts to answer the principal question as to whether Rosenzweig’s thought belongs to the tradition of Kantian philosophy.The author addresses the Rosenzweig’s interpretation of Kant’s concept of freedom as a hermeneutical cipher to expose some of his considerations on human nature. Rosenzweig acknowledges Kant’s achievement in attributing a human act to the major fundament, which will save a human from the universal...

... of Sciences. Life sci­ences. 2020. Vol. 495. P. 607—611. doi: 10.31857/S2686738920060207. 4. Cremonini E., Zonaro E., Donini M. et al. Biogenic selenium nanoparticles: char­acterization, antimicrobial activity and effects on human dendritic cells and fibro­blasts // Microbial Biotechnology. 2016. Vol. 9, № 6. P. 758—771. doi: 10.1111/1751- 7915.12374. 5. Perfileva A. I., Nozhkina O. A., Graskova I. A. et al. Selenium nanocomposites ha­ving polysaccharid matrices stimulate growth ...

... assess the toxicological characteristics of materials as well as develop methods for their therapeutic use. A study was conducted to evaluate the cytotoxicity of composite nanoparticles (nanostars) and micromaterials (microdisks) against Jurkat, Huh7 cell cultures, and human mononuclear cells in in vitro conditions. A concentration-dependent cytotoxic effect of nanoparticles was observed. At the same time, microdisks did not exhibit any toxic effects on the studied cells. The potential of using nano- ...

... studying the category of home, which actualizes essential spiritual and moral meanings, and its variant, the anti-home. Analyzing the spatial organization of V. G. Korolenko’s story Yashka reveals that the vertical and horizontal arrangement of prison cells forms the traditional oppositions of “top — bottom” and “right — left” characteristic of Slavic mythology. A corresponding character system is constructed: the protagonist, Yakov, who disturbs everyone with his loud, persistent knocking ...

... significantly increased the optical density of the initial solution to 0.087, more than doubling the results compared to other conventional media and proving advantageous for industrial-scale cultivation. The study recommends using a reduced initial cell concentration of Chlorella sp. B1 in the inoculum, followed by cultivation at 32 °С with enhanced illumination (52 W) and the addition of 0.9 g/L of carbon dioxide for three days in a 500 mL flat-panel photobioreactor. Shamaev N.D., Kuryntseva ...

.... Journal of Biosemiotics , 1 (1), pp. 223—238. Pattee, H. H., 2012a. How Does a Molecule Become a Message? In: Laws, Lan­guage and Life. Biosemiotics . Vol. 7, pp. 55—67, https://doi.org/10.1007/978-94-007-5161-3_3 . Pattee, H. H., 2012b. Cell Psychology: An Evolutionary Approach to the Symbol-Matter Problem. In: Laws, Language and Life. Biosemiotics . Vol. 7, pp. 165—179, https://doi.org/10.1007/978-94-007-5161-3_11 . Peirce, C. S. and Welby-Gregory, V. (Lady Welby), 1977. Semiotic ...

Artificial electromagnetic fields are a byproduct of the electrical or elec­tronic devices as an inevitable consequence of the modern scientific and tech­nical progress, and at the same time poorly studied environmental impact fac­tor. Research of current levels and spatial distribution of electromagnetic fields in Kaliningrad aimed at mapping, defining statistically significant characteristics for types of land use and building types, revealing abnormal areas and their correspondence to hygienic...

... 878—886. 21. Nemati S., Banan R., Alizadeh A. Ultrasonographic evaluation of long-term re­sults of nasal tip defatting in rhinoplasty cases // Laryngoscope. 2013. Vol. 123, № 9. P. 2131—2135. 22. Wortsman X. Sonography of facial cutaneous basal cell carcinoma: a first-line ima­ging technique // J. Ultrasound Med. 2013. Vol. 32, № 4. P. 567—572. 23. Meyer N., Lauwers-Cances V., Lourari S. et al. High-frequency ultrasonography but not 930-nm optical coherence tomography reliably evaluates ...

The article focuses on the neuropsychology of hearing and the impact of learning on the development of musical ear in various musical fields. The goal is to determine whether there is a difference in the development of tone and interval sound perception among musicians in different areas of study. Zero hypothesis (H0): The lack of dependence of the perception accuracy of sounds and intervals (absolute and relative musical ear) on the field of mu­sical training. Alternative hypothesis (H1): The accuracy...

... Measured by Quantitative Elasticity Parameters in Rats With Immune Hepatitis // J Ultrasound Med. 2016. Vol. 35 (6). P. 1223—1231. doi: 10.7863/ultra.15.03001. Garkavenko O., Emerich D. F., Muzina M. et al. Xenotransplantation of neonatal porcine liver cells // Transplant Proc. 2005. Vol. 37 (1). P. 477—480. doi: 10.1016/ j.transproceed.2004.12.183. Niehues S. M., Unger J. K., Malinowski M. et al. Liver volume measurement: rea­son of the difference between in vivo CT-volumetry and intraoperative ...

... Sci. 1989. Vol. 6. P. 867—875. 24. Waser P. M. The spectral sensitivity of the eye of Aplysia californica // Comparative Biochemistry and Physiology. 1968. № 27. P. 339—347. 25. Zylstra U. Distribution and ultrastructure of epidermal sensory cells in the freshwater snails Lymnaea stagnalis and Biomphalaria pfeifferi // Neth. J. Zool. 1972. Р. 283—298. Sudoplatov K. A., Shirshikova N. V., Zhukov V. V. Lymnaea stagnalis (L.), shadow reflex, photosensitive pigment, absorption spectrum. ...

... weight and volumetric graft volume by an analysis of blood content in living donor liver grafts // Transplant. Proc. 2002. Vol. 34, № 8. P. 3293—3294. 26. Garkavenko O., Emerich D., Muzina M. et al. Xenotransplantation of neonatal porcine liver cells // Transplant. Proc. 2005. Vol. 37, № 1. P. 477—480. 27. Изранов В. А., Казанцева Н. В., Мартинович М. В. и др. Оценка точности вычисления стандартного объема при ...

... человека с официальным списком русских эквивалентов / под ред. В. В. Банина, В. Л. Быкова. М., 2009. Gordova V. S., Soloveva L. M., Sergeeva V. E., Izranov V. A. medical histology, tissue, cells, teaching 49-56

Research works aimed at assessing the interaction in the host-parasite system, pay attention to the products of the vital activity of the parasite. Hemozoin is one of the most promising metabolites that can be used for new methods of parasite diagnostics and treatment. It is known that hemozoin is produced by parasites causing schistosomiasis and malaria. Recent research has shown that hemozoin is produced by the hepatic trematode Opisthorchis felineus, but the effects associated with the presence...

An excess of silicon compounds in the body leads to systemic deficiencies. Regardless of the way by which silicon compounds (silicon dioxide, asbestos, silicon, and silicon nanoparticles) enter the body, they always have a marked effect. It is established that these compounds play a part in the pathogenesis of renal diseases. The article provides a morphological description of the renal corpuscles of laboratory mice (n=10) during three months’ ad libitum administration of silicon in a concentration...

.... № 4. С. 57—61. 20. Шилов В. Н. Молекулярные механизмы структурного гомеостаза. М., 2006. 21. Аrantes-Oliveira N., Apfeld J., Dillin A., Kenyon C. Regulation of life-span by germline stem cells in Caenorhabditis elegans // Science. 2002. Vol. 295(5554). P. 502—505. 22. Finch C. E., Tanzi R. E. Genetics of aging // Scii. 1997. Vol. 278. P. 407—410. Areshidze D., Timchenko L. entropy, biological system, liver, pathology, adaptation ...

This article describes the effect of three hormonal specimens — two analogues of sex steroid hormones (progesterone and testosterone) and a glycocorticoid hormone prednisolone (dehydrogenated analogue of hydrocortisone) —on the process of regeneration of freshwater planarian Dugesia lugubris Schmidt, 1861. The hormonal specimens differing on chemical nature and physiological activity have differently directed effect on the processes of regeneration. The rate of proliferation generally depends on...

... products of lipid peroxidation resulting from chronic ethanol administration // Alcohol & Alcoholism. 1999. Vol. 34. № 6. P. 842—850. 6. Kusano C., Ferrari B. Total antioxidant capacity: a biomarker in biomedical and nutritional studies // Journal of cell and molecular biology. 2008. Vol. 7. P. 1—15. 7. Мисин В. М., Сажина Н. Н., Короткова Е. И. Сравнительный анализ суммарного содержания антиоксидантов и их активности ...

... 105—110. 7. Rice-Evans C. A., Miller N. J., Paganga G. Antioxidant properties of fenolic compounds // Trends in plant science. 1997. Vol. 2, № 4. P. 152—159. 8. Skaper S. D., Fabris M., Ferrari V. et al. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by gluthatione depletion cooperative effects of ascorbic acid // Free Radical Biology and Medicine. 1997. Vol. 22, № 4. P. 669—678. 9. Яшин А. Я., Яшин Я. И. Новый ...

The article presents the preliminary results concerning the quantitative content of nitrogen-fixing, cellulose-eliminating microorganisms and microorganisms using the mineral forms of nitrogen and microscopic fungi in Kaliningrad soils under different environmental conditions. 1. Arun Gurpa , Vinay K . Singh , G .   N . Qazi , Anil Kumar . Gluconobacter oxydans : Its Bio­tech­nological Applications // Mol. Microbiol. Biotechnol. 2001.Vol. 3. P. 445—456. 2. Кустова Н .   А . Трансформация...

... Biophys. 1996. V. 332. P. 183—186. 17. Chalker-Scott L. Environmental Significance of Anthocyanins in Plant Stress Responses // Photochemistry and Photobiology. 1999. V. 70. P. 1—9. 18. Rao M.   V., Davia K.   R. The physiology of ozone induced cell death // Planta. 2001. V. 213. Р . 682—690. 19. Gosslau A., Rensing L. Oxidativer Stress, altersabhängige Zellschädigungen und antioxidative Mechanismen // Z. für Gerontologie und Geriatrie. 2002. V. 35. S .  139—150. 20....

The article presents the preliminary results concerning the quantitative content of nitrogen-fixing, cellulose-eliminating microorganisms and microorganisms using the mineral forms of nitrogen and microscopic fungi in Kaliningrad soils under different environmental conditions. 1. Влияние автотранспорта на окружающую среду в городах России. URL : www.transpenv.org.ru 2. Доклад о состоянии и об охране окружающей среды Калининградской области в 2002 г . / Упр. природ. ресурсов и охраны окружающей...

... эпидемиологиче­ская значимость // Рыбное хозяйство. Сер. Аквакультура. Информ . пакет . 1997. Вып . 1. С . 1—16. 9. Einszporn-Orecka T. Cytological evaluation of the peripheral blood cell and hemopoietic organs in pestis anguillarum of eels // Acta Ichthyologica et Piscatoria. 1976. Vol . 6, fasc . 1. P . 67—81. 10. Определитель бактерий Берджи / под ред. Дж. Хоулта. М ., 1997. Т ....