Natural and medical sciences

2019 Issue №1

Liver elastography techniques and the problems of Russian terminology

Abstract

In this review, we approach Russian terminology in elastography by discussing elastography technique classifications using terms that take into account the essence of physical patterns underlying various elastography techniques. Elastography techniques used in clinical practice are divided into four groups: strain elastography, transient elastography, point shear wave elastography, and 2D shear wave elastography. Based on physical principles, two types are identified: strain elastography and shear wave elastography. Since the techniques are founded on different physical principles, we recommend combining these techniques to improve to improve diagnostic accuracy. We propose a Russian glossary of term used in elastography. An ef­fective use of the glossary requires Russian terminology in elastogrgraphy to be included in the guidelines of the Russian Association of Experts of Ultra­sonic Diagnostics in Medicine, similar to those provided by the EFSUMB.

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Case study: treatment of a patient with Т- cell lymphoma (delta-gamma-variant)

Abstract

In this article, we present a clinical case of a patient with T-cell lympho­ma (delta-gamma variant) complicated by neuroleukemia. We performed a dif­ferential diagnosis from other lymphoproliferative diseases. Our diagnosis was based on trepanobiopsy and immunophenotyping data: delta-gamma-T/NK-cell lymphoma, hepatolienal form. The first NHL-BFM 90 protocol block was obtained. We performed a whole body PET/CT scan and a myelogram to con­firm the diagnosis. Since therapy was ineffective, we conducted two courses of second-line therapy (R-ICE) and received a partial response. Further, alloge­neic hematopoietic stem cell transplantation was recommended. After two R-ICE courses, the patient received supportive polychemotherapy (Rituximab + + Gem­zar), without progression. Six months later, the patient's condition wors­ened. We performed spinal puncture and diagnosed neuroleukemia. It was recom­mended that the patient received a specific course of polychemother­apy. There­fore, patients diagnosed with hepatolienal T-cell lymphoma, in view of the highly aggressive disease course, are recommended to undergo allogene­ic trans­plantation of hematopoietic stem cells as early as possible.

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