IL-1β and IL-8 influence on cytoprotective mechanisms in liver tissue in morbid obesity patients with comorbidities
... subclinical inflammation in obesity contributes to the development of oxidative stress and mitochondrial dysfunction, which underlie the pathogenesis of obesity-associated diseases, i. e., type 2 diabetes and NAFLD.
The study included 130 patients with morbid obesity and comorbid diseases (NAFLD and type 2 diabetes). The gene expression level (NRF2, TFAM, AMPK, HSF1, HSP70) was determined by real-time PCR and the detection of protein products was confirmed by Western blot. The concentration of cytokines ...
Application of spatial analysis of morbidity and mortality from COVID-19 (the case of the Pskov region)
... pandemic, set large-scale tasks for creating and improving mathematical and information technologies that operate spatial data in statistical analysis and forecasting. The regional level is seen as a suitable choice for spatial analysis of COVID-19 morbidity and mortality due to the availability of statistics, as well as data on geographical patterns, characteristics of the distribution space (population density, concentration in one city, density of the transport network, distance to the focus ...
Climate change and the dynamics of vector-borne disease rate in the Kaliningrad region
This article considers the morbidity of vector-borne infections in the Kaliningrad region against the background of regional climate change. The author points out the increasing prevalence of Lyme disease in 1995—2008 and emphasises the role of abnormal weather conditions in ...
Achievements and challenges in the Kaliningrad healthcare system during “real socialism”
... which mitigated this tendency, included high indicators of provision of medical workers in the region, a closer connection between rural and urban healthcare and a younger average age of the population.
Mankevich D.V.
Kaliningrad region, medicine, morbidity, oncology, public healthcare, USSR
59-69
10.5922/sikbfu-2022-4-6
Disturbance of the vaginal microbiome and the risk of HIV infection in women: analysis of scientific studies
... in which continuous cell turnover occurs, a process that requires cells to differentiate without provoking an inflammatory immune response. This defines a susceptibility unique to women of reproductive age, who are at disproportionate risk of morbidity and mortality associated with viral pathogens such as HIV infection.
Khryanin А.А., Knorring G. Yu., Bocharova V.K
vaginal microbiome, bacterial vaginosis, HIV infection, female reproductive tract, women's health
89-97
Physical foundations of liver elastography
... диагностика. 2017. № 6. С. 11—24.
Karlas
T., Dietrich A., Peter V. et al. Evaluation of transient elastography, acoustic radiation force impulse imaging (ARFI), and enhanced liver function (ELF) score for detection of fibrosis in morbidly obese patients // PLoS One. 2015. Vol. 10 (11). P. e0141649. doi: 10.1371/journal.pone.0141649.
Bert F., Stahmeyer J. T., Rossol S. Ultrasound Elastography Used for Preventive Non-Invasive Screening in Early Detection of Liver Fibrosis // J Clin ...
Immune reconstitution inflammatory syndrome (IRIS) in HIV-infected patients: risk factors, clinical features, outcomes, prevention
... Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents Recommendations from CDC, the National Institutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America // Morbidity and Mortality Weekly Report. 2009. Vol. 58, № RR-4. URL: www.cdc.gov/mmwr (дата обращения: 21.12.2011).
10. Барлет Д., Галант Д., Фам П. Клинические аспекты ВИЧ-инфекции. М., 2010....
