Hemozoin accumulation associated with Opisthorchis felineus infection and the analysis of its role in changing the bile ducts microbiota
... opisthorchiasis. Samples of mature forms of O. felineus are also included in the study. In accordance with the results obtained, hemozoin accumulates mainly in the liver during the invasion of O. felineus. The invasion of O. felineus leads to an increase in the alpha diversity of the bile duct microbiota in animals, and this effect is not associated with the presence of hemozoin in the bile ducts. Metagenomic analysis revealed that the most representative taxa in the mature forms of O. felineus are Sphingomonas, Prevotella,...
Classification and characterisation of a new antimicrobial peptide
... achieved in AMP research, revealing the potential of these compounds as alternatives to traditional antibiotics. Due to the diverse mechanisms of action and a wide range of antibacterial activity, AMP provides new opportunities for preventing and treating ... ... molecular formula is C64H96N21O15S0, with protein binding potential (Boman index) at 3.44 kcal/mol. The peptide can form an alpha helix. The resulting peptide can be classified as a synthesised cationic hydrophobic alpha-helical antimicrobial polypeptide....
