Development and synthesis of a non-specific immunomodulating peptidomimetic
... routes. Low bioavailability following oral administration further complicates the clinical use of peptides, especially in chronic diseases requiring patient-friendly treatment regimens. The aim of the study was to develop, synthesize, and characterize a peptidomimetic for oral administration with nonspecific immunomodulatory activity, as well as to assess its cytotoxicity and effect on DC proliferation. The object of the study was a peptidomimetic designated CD-17 with the following amino acid sequence: ...
