Cytokine-induced regulation of maturation, differentiation, and apoptotic death of immune memory T-lymphocytes
... processes of apoptotic death to prevent the development of autoimmune and neoplastic reactions. T-lymphocytes of immune memory are under strict control from the immune system.
The role of γc-cytokines (IL-2, IL-7, and IL-15) in the regulation of maturation, differentiation, and apoptotic death of memory T-lymphocytes under in vitro cultivation conditions was evaluated.
The study revealed the ability of γc-cytokines to increase the content of CD3+HLA-DR+CD95+ T cells in the effector populations ...