Influence of hematopoietic growth factors on the activation status and functional activity of human T-lymphocytes
6. Larbi A., Fulop T. From «Truly Naïve» to «Exhausted Senescent» T Cells: When Markers Predict Functionality // Cytometry Part A. 2014. Vol. 85A. P. 25—35.
7. Briend E., Colle J. H., Fontan E. et al. Human glycoprotein HGP92 induces cytokine synthesis in mouse mononuclear phagocytes // Int Immunol. 1995. Vol. 7. P. 1753—1761.
8. Brugger W., Mocklin W., Heirnfeld S. et al. Ex vivo expansion of enriched peripheral blood CD34+ progenitor cells by stem cell factor, interleukin-1a, ...
IL-1β and IL-8 influence on cytoprotective mechanisms in liver tissue in morbid obesity patients with comorbidities
... with morbid obesity and comorbid diseases (NAFLD and type 2 diabetes). The gene expression level (NRF2, TFAM, AMPK, HSF1, HSP70) was determined by real-time PCR and the detection of protein products was confirmed by Western blot. The concentration of cytokines (IL-1β, IL-8) was measured in plasma by multiplex analysis in flow fluorometry format. It was demonstrated that an increase in the concentration of pro-inflammatory cytokines IL-1β, IL-8 in blood plasma was associated with the development ...
Cytokine-induced regulation of maturation, differentiation, and apoptotic death of immune memory T-lymphocytes
Thus, maintaining homeostatic concentrations of γc-cytokines plays an important role in maintaining the normal functioning of the immune system by maintaining the balance of homeostatic proliferation and apoptotic death. We also noted that cytokine imbalance contributes to an increase in the surface expression of late activation molecules (HLA-DR) and apoptosis (CD95), which is necessary to control excessive proliferation of lymphocytes, and, ultimately, prevents the breakdown of immune ...