Disturbance of the vaginal microbiome and the risk of HIV infection in women: analysis of scientific studies
... influence the local immune cell population and inflammation status. While a low diversity microbial composition dominated by Lactobacillus crispatus is associated with a reduced risk of HIV infection, a high microbial diversity environment associated with bacterial vaginosis increases the risk of HIV infection. Given the important role of the vaginal microbiome in determining HIV susceptibility, changing the microbiome towards Lactobacillus spp. dominance is an attractive additional strategy to reduce the incidence ...
